Twin Pregnancies

Risks, Complications, and Management Methods

Twin pregnancies increase excitement for couples but also require greater medical attention and care. While most twin pregnancies result in healthy outcomes, certain risks and complications are more common compared to singleton pregnancies.

Common Complications in Twin Pregnancies

1. Preterm Labor and Delivery

Preterm birth is defined as delivery before 37 weeks of gestation. While delivery in singleton pregnancies usually occurs after 39 weeks, the average gestational age in twin pregnancies decreases to around 36 weeks. The risk of preterm birth is higher in twin pregnancies and often begins with premature rupture of membranes. Preterm births may lead to various health problems in newborns.

2. Low Birth Weight

Low birth weight is defined as a birth weight of less than 2,500 grams and is commonly associated with preterm birth. In deliveries occurring before 32 weeks, infants may weigh less than 1,500 grams, and complications such as intellectual disability, cerebral palsy, and vision or hearing problems are more frequently observed.

3. Intrauterine Growth Restriction (IUGR)

In twin pregnancies, fetal growth may proceed normally until 30–32 weeks. After this period, placental insufficiency may occur, leading to slowed growth. Therefore, fetal development in twin pregnancies should be closely monitored.

4. Preeclampsia

Preeclampsia is a condition that occurs in the second half of pregnancy and is characterized by high blood pressure and proteinuria. The risk of preeclampsia is twice as high in twin pregnancies. In triplet pregnancies, this rate can increase up to 50%. Preeclampsia poses serious risks for both the mother and the babies, making regular monitoring and adequate care essential.

5. Gestational Diabetes

Gestational diabetes is a type of diabetes that develops for the first time during pregnancy and is more common in twin pregnancies. This is due to increased placental hormone production, which raises insulin resistance. As a result, blood glucose regulation becomes more difficult, posing risks for both mother and babies.

6. Placental Abruption

Placental abruption is the premature separation of the placenta from the uterine wall and is three times more common in twin pregnancies. It usually occurs in the third trimester and may require urgent medical intervention.

7. Fetal Loss

Although fetal loss is rare in twin pregnancies, when it occurs in dichorionic pregnancies (each fetus has its own placenta), intervention is usually not required. However, in monochorionic pregnancies (twins sharing the same placenta), fetal loss can pose serious risks and may necessitate preterm delivery.

8. Cesarean Delivery

Cesarean delivery is not mandatory in twin pregnancies. However, it may be preferred depending on the fetal presentation. Criteria for vaginal delivery include:

Pregnancy should be beyond 32 weeks.
The presenting fetus should be larger.
The first fetus should be in the head-down position.
The second fetus may be in cephalic or breech presentation.
The second fetus should be smaller.
There should be no cephalopelvic disproportion (CPD).

9. Twin-to-Twin Transfusion Syndrome (TTTS)

TTTS is a complication seen in twins who share the same placenta. Due to vascular connections within the placenta, one fetus (the recipient) receives more blood, while the other (the donor) receives less. This can lead to excessive blood volume, heart failure, and polyhydramnios in the recipient fetus, while anemia and oligohydramnios may develop in the donor fetus. TTTS occurs in approximately 15% of monochorionic twin pregnancies and is a serious condition.

TTTS

TTTS is usually diagnosed during ultrasound examination. Diagnostic findings include fetal sex, discrepancies in biometric measurements, differences in amniotic sac size, differences in umbilical cord thickness, the presence of a single placenta, polyhydramnios in the recipient fetus, and oligohydramnios in the donor fetus.

Maternal Findings

Rapid uterine enlargement

Excessive increase in abdominal size for gestational age

Abdominal pain, tension, and contractions

Sudden excessive weight gain

Early swelling of the hands and feet

TTTS Treatment Options

Findings

Rapid uterine enlargement

Excessive increase in abdominal size for gestational age

Abdominal pain, tension, and contractions

Sudden excessive weight gain

Early swelling of the hands and feet

TTTS Treatment Options

Previously considered untreatable, TTTS can now be managed with certain medical interventions. Treatment options include amnioreduction (removal of excess amniotic fluid) and laser therapy. Laser treatment interrupts placental vascular connections and achieves success in approximately 60% of affected pregnancies. Monitoring fetal lung maturation and planning early delivery when appropriate are also among treatment strategies.

Twin pregnancies are special conditions that require closer monitoring and care for both the mother and the babies. Although risks may be higher, a healthy pregnancy and delivery are possible with regular medical follow-up and appropriate treatment methods. Routine ultrasound examinations throughout pregnancy allow early detection of complications and timely interventions. Expectant mothers with twin pregnancies should maintain close communication with their physicians and strictly follow medical recommendations.